Software:TPP

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[[image:TPP_overview.gif]] [[image:TPP_overview.gif]]
-Software contained in the TPP: 
 +==Getting the software==
-==Probability Assignment and Validation==+===[[TPP:Windows Cygwin Installation|Installing on a Windows System]]===
 + 
 +===Source code (For Linux systems)===
 +The latest source code package can be found [http://sourceforge.net/project/showfiles.php?group_id=69281&package_id=126912 here], on the Sashimi project site on SourceForge.
 + 
 +===[[TPP:Installing on Mac OSX|Mac OSX Installation guide]]===
 + 
 +<!-- <P>Download source from local site: <a href="./software/TPP_v2.9.7_GALE.zip">TPP_v2.9.7_GALE.zip</a></P> -->
 +<!-- <P>Download cygwin binaries: <a href="windows.php">Windows installation</a></P> -->
 + 
 + 
 +<!-- <P>Download source from Web: <a href="http://sourceforge.net/project/showfiles.php?group_id=69281">Sourceforge Page</a><br> -->
 +<!-- <em>Note: On the web you might find a newer version of this software.</em></P> -->
 + 
 + 
 +==Software contained in the TPP==
 + 
 + 
 +===Probability Assignment and Validation===
[[Software:PeptideProphet|PeptideProphet]]: Statistical validation of spectra-to-peptide sequence, using search engine results. [[Software:PeptideProphet|PeptideProphet]]: Statistical validation of spectra-to-peptide sequence, using search engine results.
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[[Software:ProteinProphet|ProteinProphet]]: Protein identification and validation, using [[Software:PeptideProphet|PeptideProphet]] results. [[Software:ProteinProphet|ProteinProphet]]: Protein identification and validation, using [[Software:PeptideProphet|PeptideProphet]] results.
-==Protein Quantification==+===Protein Quantification===
[[Software:XPRESS|XPRESS]]: Calculation of relative abundance of proteins from MS/MS data. [[Software:XPRESS|XPRESS]]: Calculation of relative abundance of proteins from MS/MS data.
Line 20: Line 38:
[[Software:Libra|Libra]]: Four channel quantification software. [[Software:Libra|Libra]]: Four channel quantification software.
-==Graphical User Interface (GUI)==+===Graphical User Interface (GUI)===
[[Software:Petunia|Petunia]]: Petunia is the name of the TPP's web-based GUI, which presents the tools in an organized and logical manner for those who do not wish to use the command-line. [[Software:Petunia|Petunia]]: Petunia is the name of the TPP's web-based GUI, which presents the tools in an organized and logical manner for those who do not wish to use the command-line.
-==Protein ID Curation==+===Protein ID Curation===
Out2Summary - converter of SEQUEST and TurboSEQUEST *.out files into a single HTML-SUMMARY file ready for use with INTERACT Out2Summary - converter of SEQUEST and TurboSEQUEST *.out files into a single HTML-SUMMARY file ready for use with INTERACT
[[Software:Pep3D|Pep3D]]: Viewer for LC-MS and LC-MS/MS results. [[Software:Pep3D|Pep3D]]: Viewer for LC-MS and LC-MS/MS results.
-==Input Processing: mzXML Tools==+===Input Processing: mzXML Tools===
readmzXML: mzXML parser based on RAMP readmzXML: mzXML parser based on RAMP

Revision as of 23:06, 10 April 2007

The Trans-Proteomic Pipeline (TPP) is a collection of integrated tools for MS/MS proteomics, developed at the SPC.

image:TPP_overview.gif


Contents

Getting the software

Installing on a Windows System

Source code (For Linux systems)

The latest source code package can be found here, on the Sashimi project site on SourceForge.

Mac OSX Installation guide

Software contained in the TPP

Probability Assignment and Validation

PeptideProphet: Statistical validation of spectra-to-peptide sequence, using search engine results.

ProteinProphet: Protein identification and validation, using PeptideProphet results.

Protein Quantification

XPRESS: Calculation of relative abundance of proteins from MS/MS data.

ASAPRatio: Automated Statistical Analysis on Protein Ratio.

Libra: Four channel quantification software.

Graphical User Interface (GUI)

Petunia: Petunia is the name of the TPP's web-based GUI, which presents the tools in an organized and logical manner for those who do not wish to use the command-line.

Protein ID Curation

Out2Summary - converter of SEQUEST and TurboSEQUEST *.out files into a single HTML-SUMMARY file ready for use with INTERACT

Pep3D: Viewer for LC-MS and LC-MS/MS results.

Input Processing: mzXML Tools

readmzXML: mzXML parser based on RAMP

MsXML2Other: mzXML to SEQUEST dta, MASCOT generic and Micromass pkl converter

mzStar: SCIEX/ABI Analyst format to mzXML converter

ReAdW: ThermoFinnigan Xcalibur format to mzXML converter

RAMP: mzXML data parser

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