Glyco-peptide

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2008-08-22 RA proposes effort to generate peptide lists for dirty peptide synthesis. Tentative deadline is 08-29.

Links:

 Glyco-peptide TODO list
 Export questions discussion list


2008-08-22 [late] emailed the following people, seeking data

Simon

- responded.  Does not have any relevant data.  Has database of existing transitions and ordered peptides, perhaps this can be used to filter list.

Safia

- responded.  She has already given me 2 large sets of data from Breast Cancer cell lines/tissue.  The first is part of the existing GlycoAtlas build,
              the second will be incorporated.

Yong (Z)

- responded.  He had already contributed some data, but has additional urine (1800 peptides) and ovarian cell glycocapture (400 peptides) samples.  Sent 
              sample  information, will incorporate into new build.

Kelly

- responded.  Has given a pancreas dataset in the past, may have generated data in set that Julian gave to Eric.  Contributed breast-cancer IEF samples.  Has now also contributed an additional pancreas dataset.

Hamid

- responded. Contributed several test datasets created while testing HPINs technology.  These use a large serum glycocapture sample prepared by Kelly.

Julian

- responded.  Had recently given dataset to Eric, which will be incorporated.

Bernd (W)

- responded.  Created a separate list from his cell surface data, will be responsible for merging and prioritizing the lists from Jingchun, himself, and me.

Johan

- responded.  Has contributed large serum (IEF) datasets in the past, no new data. 

Ralph

- responded.  Has only mouse data, has contributed in the past and is basis for mouse glyco build.

Ruth

- responded.  Has only mouse data, will transfer to ftp servers.  Suggested using mouse/human ortholog data.

Silvia

- responded, contributed Colon cancer data.


2008-08-26 Jingchun announces he has generated list of 3464 glycopeptides from putative cancer biomarkers.

2008-08-27 Bernd announces he has generated a list of peptides from surface proteins, proposes common export format.

2008-08-28 Discuss export details with Bernd

2008-08-28 Discover that Breast cancer search not compatible with Atlas Build, will research with XTandem.

2008-08-28 Received last of human data

2008-08-31 Received one batch of mouse glyco data, more to come?

2008-09-01 Finished global ProteinProphet, started build proper

2008-09-01 Ran export script against unipep data, send email to Bernd.

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