Software:Mayu

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-[placeholder]+== Mayu ==
 +'''Protein Identification False Discovery Rates'''
 + 
 +Mayu is a software package for the analysis of (large) mass spectrometry-based shotgun proteomics data sets. Mayu determines protein identification false discovery rates (protFDR), peptide identification false discovery rates (pepFDR) and peptide-spectrum match false discovery rates (mFDR) using a novel robust and fast strategy.
 + 
 +Mayu is not a search engine and works with any* peptide-spectrum match discriminant score derived from a database search.
 + 
 +This software is licensed under the CC-GNU GPL version 2.0 or later. This software and associated documentation is provided "as is" and there is no warranty for this software.
 + 
 +<nowiki>*</nowiki> if this discriminant score is compatible with target decoy searching
 + 
 + 
 +'''Software'''
 + 
 +For running Mayu install a perl interpreter and run the software from the unpacked zip file on a command line. See the manual, pdf for more details.
 + 
 + 
 +'''Download'''
 + 
 +<ul>
 + <li>manual</li>
 + <li>software package</li>
 + <li>example data set</li>
 + <li>perl script to create target decoy databases</li>
 + </ul>
 + 
 + 
 + 
 +'''Features'''
 + 
 +<ul>
 + <li>provides&nbsp;false discovery rates not
 +only on peptide-spectrum match level (mFDR) but also
 +on&nbsp;protein identification (protFDR) and&nbsp;peptide
 +identification (pepFDR) level</li>
 + <li>false discovery rates for single hits (single
 +peptide-spectrum match protein identifications) and all but single hits
 +(protein identifications with more than one peptide-spectrum match)</li>
 + <li>analysis in dependence of the amount of data</li>
 + <li>R plots</li>
 + <li>provides tables for each input file that relate
 +the discriminant score (e.g. PeptideProphet, xcorr, mascot ion
 +score,...) to a peptide-spectrum match false discovery rate</li>
 + </ul>

Revision as of 15:18, 28 October 2008

Mayu

Protein Identification False Discovery Rates

Mayu is a software package for the analysis of (large) mass spectrometry-based shotgun proteomics data sets. Mayu determines protein identification false discovery rates (protFDR), peptide identification false discovery rates (pepFDR) and peptide-spectrum match false discovery rates (mFDR) using a novel robust and fast strategy.

Mayu is not a search engine and works with any* peptide-spectrum match discriminant score derived from a database search.

This software is licensed under the CC-GNU GPL version 2.0 or later. This software and associated documentation is provided "as is" and there is no warranty for this software.

* if this discriminant score is compatible with target decoy searching


Software

For running Mayu install a perl interpreter and run the software from the unpacked zip file on a command line. See the manual, pdf for more details.


Download

  • manual
  • software package
  • example data set
  • perl script to create target decoy databases


Features

  • provides false discovery rates not only on peptide-spectrum match level (mFDR) but also on protein identification (protFDR) and peptide identification (pepFDR) level
  • false discovery rates for single hits (single peptide-spectrum match protein identifications) and all but single hits (protein identifications with more than one peptide-spectrum match)
  • analysis in dependence of the amount of data
  • R plots
  • provides tables for each input file that relate the discriminant score (e.g. PeptideProphet, xcorr, mascot ion score,...) to a peptide-spectrum match false discovery rate
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