Terry's compbio links

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Contents

Terry Farrah's Computational Biology Links

ISB specific stuff

Mail Intranet

Terry's notes on how to perform a Peptide Atlas build

Additional notes on PeptideAtlas software

Using the PeptideAtlas SearchProteins tab

Notes on searching and TPP usage from the Unix command line at ISB

TPP testimonials

Notes on database programming for SBEAMS

Processing glycopeptide data

SBeams: SPC's experimental data storage system. Go here to run an SBeams test drive.

db.systemsbiology.net: Developer's back door into SBeams. Go here to contribute data.

db.systemsbiology.net/devTF/sbeams/cgi/main.cgi Terry's SBeams software development sandbox

Proteomics stuff

Peptide Atlas: a multi-organism, publicly accessible compendium of peptides identified in a large set of tandem mass spectrometry proteomics experiments.

TPP developers' group, TPP users' group

SpectraST spectrum viewer

NIST Peptide Mass Spectral Libraries

Mayu: analysis of (large) mass spectrometry-based shotgun proteomics data sets. Mayu determines protein identification false discovery rates (protFDR), peptide identification false discovery rates (pepFDR) and peptide-spectrum match false discovery rates (mFDR) using a novel robust and fast strategy. Developed by Lukas Reiter.

X!Tandem parameters; X!Tandem home page

InsPecT sequence search engine

PRIDE PRoteomics IDEntification database

Terry's blog on improving proteomics peptide and protein identifications

General computational biology stuff

The Pipe Protein Information and Property Explorer, developed at ISB by Hector Ramos

Swiss-Prot curated protein sequence database

Amigo: browser for the Gene Ontology database

ftp://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/complete: Download Swiss-Prot and other UniProt databases, updated every 3 weeks. UniProtKB/Swiss-Prot purportedly contains the canonical human proteome (The UniProt Consortium, "The Universal Protein Resource (UniProt) 2009, Nucleic Acids Research 2008 1-6) consisting of 20,325 entries for UniProt release 14.0. Swiss-Prot release 56.6 of 16-Dec-08 contains 20,333 human proteins.

[ftp://ftp.ncbi.nih.gov/repository/UniGene/Homo_sapiens: Download NCBI's UniGene human. Contains chromosomal information, among many other data.

http://www.broad.mit.edu/~mclamp/alpheus/ Gene content of human genome]: which Ensembl entries are real genes and which are not, according to Clamp et al, "Distinguishing protein-coding and noncoding genes in the human genome", PNAS December 4, 2007, 19428-19433, Vol. 104 No. 49.

General programming stuff

Unix shell: bash/tcsh syntax differences

Bash: Bash shell reference manual, Bash tips, Bash tests and comparators.

Sed: Nice sed (stream editor) reference sed one-liners

Vim: A Byte of Vim, the text editor. Sweet little Vim recipes.

Perl: Steve Litt's Perl's of Wisdom, Perl tutorials, and www.cs.cf.ac.uk/Dave/PERL/, another nice Perl reference.

Regular expressions in Perl

Python: www.python.org/doc: Helpful links for Python programmers.

svn: One-page version of the subversion book.

gnu screen: One-page ref manual. Screen allows you to run several terminal sessions from one window, and allows sessions to persist after you close the window. Very handy if you want to take your work home with you -- close windows, then resume screen from your home computer.

A few other Links

ReligiousTolerance.org: I saw one intelligently written article there. Their purpose is to provide unbiased essays on various topics.

Comic of the observable universe, from top to bottom

Personal tools