Terry's compbio links

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Contents

Terry Farrah's Computational Biology Links

ISB specific stuff

Terry's notes on how to perform a Peptide Atlas build

The ISB Unix user's expert guide to tandem MS sequence searching and TPP usage

SBeams: SPC's experimental data storage system. Go here to run an SBeams test drive.

db.systemsbiology.org: Developer's back door into SBeams. Go here to contribute data.

db.systemsbiology.net/devTF/sbeams/cgi/main.cgi Terry's SBeams software development sandbox

Proteomics stuff

Peptide Atlas: a multi-organism, publicly accessible compendium of peptides identified in a large set of tandem mass spectrometry proteomics experiments.

TPP developers' group, TPP users' group

Mayu: analysis of (large) mass spectrometry-based shotgun proteomics data sets. Mayu determines protein identification false discovery rates (protFDR), peptide identification false discovery rates (pepFDR) and peptide-spectrum match false discovery rates (mFDR) using a novel robust and fast strategy. Developed by Lukas Reiter.

X!Tandem parameters; X!Tandem home page

InsPecT sequence search engine

PRIDE PRoteomics IDEntification database

Terry's blog on improving proteomics peptide and protein identifications

General computational biology stuff

Swiss-Prot curated protein sequence database

ftp://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/complete: Download Swiss-Prot and other UniProt databases, updated every 3 weeks. UniProtKB/Swiss-Prot purportedly contains the canonical human proteome (The UniProt Consortium, "The Universal Protein Resource (UniProt) 2009, Nucleic Acids Research 2008 1-6) consisting of 20,325 entries for UniProt release 14.0. Swiss-Prot release 56.6 of 16-Dec-08 contains 20,333 human proteins.

[ftp://ftp.ncbi.nih.gov/repository/UniGene/Homo_sapiens: Download NCBI's UniGene human. Contains chromosomal information, among many other data.

http://www.broad.mit.edu/~mclamp/alpheus/ Gene content of human genome]: which Ensembl entries are real genes and which are not, according to Clamp et al, "Distinguishing protein-coding and noncoding genes in the human genome", PNAS December 4, 2007, 19428-19433, Vol. 104 No. 49.

General programming stuff

www.python.org/doc: Helpful links for Python programmers.

Bash shell reference manual, Bash tips.

Nice sed (stream editor) reference sed one-liners

Steve Litt's Perl's of Wisdom, and www.cs.cf.ac.uk/Dave/PERL/, another nice Perl reference.

Regular expressions in Perl

A few other Links

ReligiousTolerance.org: I saw one intelligently written article there. Their purpose is to provide unbiased essays on various topics.

Comic of the observable universe, from top to bottom

bash/tcsh syntax differences

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