Software:PeptideProphet

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This software is included in the current TPP distribution.

PeptideProphet is a tool for generating statistical validation of MS/MS search engines' spectra-to-peptide sequence assignments. This tool was orginally develped at the SPC, part of the ISB. PeptideProphet is now an core part of the Trans-Proteomic Pipeline software distrubtion.

Reference: Keller A, Nesvizhskii AI, Kolker E, Aebersold R. (2002) "Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search." Anal Chem 74:5383-92. download PDF

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