Software:TPP-MaRiMba
From SPCTools
TPP-MaRiMba: MRM-aware SpectraST Pipeline
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Description
MaRiMba is used to automate the creation of explicitly defined transition lists required for multiple reaction monitoring (MRM) experiments. MaRiMba creates MRM transition lists from pre-existing or custom spectral libraries, restricts output to specified proteins or peptides of interest, and filters MRM lists based on user-defined precursor peptide and product ion properties. MaRiMba can also create MRM lists containing corresponding transitions for isotopically heavy peptides, for which the precursor and product ions are adjusted according to user specifications. MaRiMba outputs the final MRM list to a text file ready for upload to a mass spectrometer.
Current Version
The current version of TPP-MaRiMba is 4.1.0. This number reflects the main TPP version number, from which TPP-MaRiMba is branched. TPP-MaRiMba is slated for public release in early 2009.
Requirments
Windows XP, Service Pack 2 or above. For instrument-to-mzXML conversion, you will need the corresponding vendor software on the same system. See Formats:mzXML for more information.
Downloading the software
The software will be available for public download from this site after publication of the manuscript (currently under review).
