Software:TIQAM
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| ==Introduction== | ==Introduction== | ||
| - | TIQAM (Targeted Identification for Quantitative Analysis by MRM)is developed as a suite of software tools to support targeted indentification and quantification using multiple reaction monitoring (MRM) mass spectum technology. More specifically, TIQAM software provided user friendly interfaces to assist process of peptide selection, transition generation and validation. The overview of the software supporting work flow is illustrated by the following figure. | + | TIQAM (Targeted Identification for Quantitative Analysis by MRM) is developed as a suite of software tools to support targeted indentification and quantification using multiple reaction monitoring (MRM) mass spectum technology. More specifically, TIQAM software provided user friendly interfaces to assist process of peptide selection, transition generation and validation. The overview of the software supporting work flow is illustrated by the following figure. |
| [[Image:TIQAMWorkFlow.jpg]] | [[Image:TIQAMWorkFlow.jpg]] | ||
| ==Detailed information and reference== | ==Detailed information and reference== | ||
Revision as of 22:29, 24 March 2008
Contents |
Introduction
TIQAM (Targeted Identification for Quantitative Analysis by MRM) is developed as a suite of software tools to support targeted indentification and quantification using multiple reaction monitoring (MRM) mass spectum technology. More specifically, TIQAM software provided user friendly interfaces to assist process of peptide selection, transition generation and validation. The overview of the software supporting work flow is illustrated by the following figure.
Detailed information and reference
The detailed information on the work flow and the application using TIQAM software for targeted quantitative analysis of Streptococcus pyogenes virulenece factors has been written and submitted to a scientific journal for review. The article title and authors are "Targeted Quantitative Analaysis of Streptococcus Pyogenes Virulenece Factors by Multiple Reaction Monitoring" by
Vinzenz Lange, Johan A. Malmström, John Didion, Nichole L. King, Björn P. Johansson, Juliane Schäfer, Jonathan Rameseder, Chee-Hong Wong, Eric W. Deutsch, Mi-Youn Brusniak, Peter Bühlman, Lars Björck, Bruno Domon and Ruedi Aebersold.
Software Information
Current TIQAM software supports Window, Mac and Linux OS and requires Java 1.6 java run time environment and MySQL community edition 5.0 database installed prior to running TIQAM software. The software will be released as Open Source under Apache2.0 license upon publication of the paper.
Contact Information
Mi-Youn Brusniak, Ph.D. 1441 North 34th St. Seattle, WA 98103 USA mbrusniak@systemsbiology.org
